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Fare Guide

Estimated lowest fares found within 7 days

The cheapest airline(s) flying from Manchester to Knoxville is American Airlines.

Travel Period: October 2024 - September 2025

The cheapest month(s) to fly from Manchester to Knoxville is November.

Oct 2024
Nov 2024
Dec 2024
Jan 2025
Feb 2025
Mar 2025
Apr 2025
May 2025
Jun 2025
Jul 2025
Aug 2025
Sep 2025

The cheapest day(s) of the week to fly from Manchester to Knoxville is Saturday.

Sun Sunday
Mon Monday
Tue Tuesday
Wed Wednesday
Thu Thursday
Fri Friday
Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Sep, 2024

Time Earliest
- Earliest
- Latest
Depart Earliest
- Earliest
- Latest
Arrive
- Earliest
- Latest
duration
- Shortest
- Longest
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05:49 MHT

10:33 TYS

4Hrs, 44m 1 Stop (CLT)
MHTManchester Airport 05:49 - TYS 10:33 4h 44m 1 Stop (CLT) Charlotte
MHTManchester Airport 05:49

CLTCharlotte Airport 09:15
CLTCharlotte Airport 08:19

TYSKnoxville Airport 10:33
4h 44m (56m)
1 Stop CLT · Charlotte 56m
American Airlines (AA 5035)Canadair Regional

American Airlines (AA 5275)Canadair Regional
American Airlines (AA 5035)
- M
- T
- W
- T
- F
- S
- S

05:49 MHT

12:12 TYS

6Hrs, 23m 1 Stop (CLT)
MHTManchester Airport 05:49 - TYS 12:12 6h 23m 1 Stop (CLT) Charlotte
MHTManchester Airport 05:49

CLTCharlotte Airport 10:59
CLTCharlotte Airport 08:19

TYSKnoxville Airport 12:12
6h 23m (2h 40m)
1 Stop CLT · Charlotte 2h 40m
American Airlines (AA 5035)Canadair Regional

American Airlines (AA 5412)Canadair Regional
American Airlines (AA 5035)
- M
- T
- W
- T
- F
- S
- S

05:55 MHT

10:08 TYS

4Hrs, 13m 1 Stop (DCA)
MHTManchester Airport 05:55 - TYS 10:08 4h 13m 1 Stop (DCA) Washington
MHTManchester Airport 05:55

DCAWashington Ronald Reagan National Airport 08:22
DCAWashington Ronald Reagan National Airport 07:48

TYSKnoxville Airport 10:08
4h 13m (34m)
1 Stop DCA · Washington 34m
American Airlines (AA 5160)Crj 700 Canadair Regional

American Airlines (AA 5207)Crj 700 Canadair Regional
American Airlines (AA 5160)
- -
- T
- W
- -
- -
- S
- -

05:55 MHT

10:01 TYS

4Hrs, 06m 1 Stop (DCA)
MHTManchester Airport 05:55 - TYS 10:01 4h 06m 1 Stop (DCA) Washington
MHTManchester Airport 05:55

DCAWashington Ronald Reagan National Airport 08:20
DCAWashington Ronald Reagan National Airport 07:48

TYSKnoxville Airport 10:01
4h 06m (32m)
1 Stop DCA · Washington 32m
American Airlines (AA 5160)Crj 700 Canadair Regional

American Airlines (AA 5207)Crj 700 Canadair Regional
American Airlines (AA 5160)
- M
- -
- -
- T
- F
- -
- S

10:59 CLT

07:48 DCA

6Hrs, 17m 1 Stop (TYS)
CLTCharlotte Airport 10:59 - DCA 07:48 6h 17m 1 Stop (TYS) Knoxville
CLTCharlotte Airport 10:59

MHTManchester Airport 05:55
TYSKnoxville Airport 12:12

DCAWashington Ronald Reagan National Airport 07:48
6h 17m (1h 21m)
1 Stop TYS · Knoxville 1h 21m
American Airlines (AA 5412)Canadair Regional

American Airlines (AA 5160)Crj 700 Canadair Regional
American Airlines (AA 5412)
- M
- T
- W
- T
- F
- -
- S

06:00 MHT

10:21 TYS

4Hrs, 21m 1 Stop (PHL)
MHTManchester Airport 06:00 - TYS 10:21 4h 21m 1 Stop (PHL) Philadelphia
MHTManchester Airport 06:00

PHLPhiladelphia International Airport 08:21
PHLPhiladelphia International Airport 07:32

TYSKnoxville Airport 10:21
4h 21m (49m)
1 Stop PHL · Philadelphia 49m
American Airlines (AA 5908)Er4 Embraer Rj145 Amazon

American Airlines (AA 5643)Canadair Regional
American Airlines (AA 5908)
- M
- -
- -
- T
- F
- -
- S

07:44 MHT

15:32 TYS

7Hrs, 48m 1 Stop (PHL)
MHTManchester Airport 07:44 - TYS 15:32 7h 48m 1 Stop (PHL) Philadelphia
MHTManchester Airport 07:44

PHLPhiladelphia International Airport 13:30
PHLPhiladelphia International Airport 09:16

TYSKnoxville Airport 15:32
7h 48m (4h 14m)
1 Stop PHL · Philadelphia 4h 14m
American Airlines (AA 5733)Er4 Embraer Rj145 Amazon

American Airlines (AA 5810)Er4 Embraer Rj145 Amazon
American Airlines (AA 5733)
- M
- -
- -
- -
- F
- -
- S

13:13 CLT

09:16 PHL

6Hrs, 26m 1 Stop (TYS)
CLTCharlotte Airport 13:13 - PHL 09:16 6h 26m 1 Stop (TYS) Knoxville
CLTCharlotte Airport 13:13

MHTManchester Airport 07:44
TYSKnoxville Airport 14:10

PHLPhiladelphia International Airport 09:16
6h 26m (2h)
1 Stop TYS · Knoxville 2h
American Airlines (AA 3118)Airbus

American Airlines (AA 5733)Er4 Embraer Rj145 Amazon
American Airlines (AA 3118)
- M
- -
- -
- -
- F
- -
- S

13:13 CLT

09:17 PHL

6Hrs, 25m 1 Stop (TYS)
CLTCharlotte Airport 13:13 - PHL 09:17 6h 25m 1 Stop (TYS) Knoxville
CLTCharlotte Airport 13:13

MHTManchester Airport 07:45
TYSKnoxville Airport 14:10

PHLPhiladelphia International Airport 09:17
6h 25m (1h 59m)
1 Stop TYS · Knoxville 1h 59m
American Airlines (AA 3118)Airbus

American Airlines (AA 5908)Er4 Embraer Rj145 Amazon
American Airlines (AA 3118)
- -
- T
- -
- -
- -
- S
- -

07:45 MHT

15:32 TYS

7Hrs, 47m 1 Stop (PHL)
MHTManchester Airport 07:45 - TYS 15:32 7h 47m 1 Stop (PHL) Philadelphia
MHTManchester Airport 07:45

PHLPhiladelphia International Airport 13:30
PHLPhiladelphia International Airport 09:17

TYSKnoxville Airport 15:32
7h 47m (4h 13m)
1 Stop PHL · Philadelphia 4h 13m
American Airlines (AA 5908)Er4 Embraer Rj145 Amazon

American Airlines (AA 5810)Er4 Embraer Rj145 Amazon
American Airlines (AA 5908)
- -
- T
- -
- -
- -
- S
- -

11:56 MHT

18:08 TYS

6Hrs, 12m 1 Stop (ORD)
MHTManchester Airport 11:56 - TYS 18:08 6h 12m 1 Stop (ORD) Chicago
MHTManchester Airport 11:56

ORDChicago O'Hare International Airport 15:30
ORDChicago O'Hare International Airport 13:35

TYSKnoxville Airport 18:08
6h 12m (1h 55m)
1 Stop ORD · Chicago 1h 55m
American Airlines (AA 3921)Embraer 170

American Airlines (AA 6101)Crj Canadair Regional
American Airlines (AA 3921)
- M
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- -
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- -
- S

12:12 MHT

19:59 TYS

7Hrs, 47m 1 Stop (CLT)
MHTManchester Airport 12:12 - TYS 19:59 7h 47m 1 Stop (CLT) Charlotte
MHTManchester Airport 12:12

CLTCharlotte Airport 18:45
CLTCharlotte Airport 14:42

TYSKnoxville Airport 19:59
7h 47m (4h 03m)
1 Stop CLT · Charlotte 4h 03m
American Airlines (AA 5457)Canadair Regional

American Airlines (AA 5206)Canadair Regional
American Airlines (AA 5457)
- -
- T
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- -
- -
- S
- -

12:12 MHT

16:25 TYS

4Hrs, 13m 1 Stop (CLT)
MHTManchester Airport 12:12 - TYS 16:25 4h 13m 1 Stop (CLT) Charlotte
MHTManchester Airport 12:12

CLTCharlotte Airport 15:17
CLTCharlotte Airport 14:42

TYSKnoxville Airport 16:25
4h 13m (35m)
1 Stop CLT · Charlotte 35m
American Airlines (AA 5457)Canadair Regional

American Airlines (AA 5269)Canadair Regional
American Airlines (AA 5457)
- -
- -
- -
- -
- -
- -
- S

12:12 MHT

19:45 TYS

7Hrs, 33m 1 Stop (CLT)
MHTManchester Airport 12:12 - TYS 19:45 7h 33m 1 Stop (CLT) Charlotte
MHTManchester Airport 12:12

CLTCharlotte Airport 18:43
CLTCharlotte Airport 14:42

TYSKnoxville Airport 19:45
7h 33m (4h 01m)
1 Stop CLT · Charlotte 4h 01m
American Airlines (AA 5457)Canadair Regional

American Airlines (AA 3119)Airbus
American Airlines (AA 5457)
- -
- -
- -
- -
- F
- -
- -

12:12 MHT

19:45 TYS

7Hrs, 33m 1 Stop (CLT)
MHTManchester Airport 12:12 - TYS 19:45 7h 33m 1 Stop (CLT) Charlotte
MHTManchester Airport 12:12

CLTCharlotte Airport 18:43
CLTCharlotte Airport 14:42

TYSKnoxville Airport 19:45
7h 33m (4h 01m)
1 Stop CLT · Charlotte 4h 01m
American Airlines (AA 5457)Canadair Regional

American Airlines (AA 3119)Airbus
American Airlines (AA 5457)
- M
- -
- -
- T
- -
- -
- -

12:12 MHT

17:23 TYS

5Hrs, 11m 1 Stop (CLT)
MHTManchester Airport 12:12 - TYS 17:23 5h 11m 1 Stop (CLT) Charlotte
MHTManchester Airport 12:12

CLTCharlotte Airport 16:17
CLTCharlotte Airport 14:42

TYSKnoxville Airport 17:23
5h 11m (1h 35m)
1 Stop CLT · Charlotte 1h 35m
American Airlines (AA 5457)Canadair Regional

American Airlines (AA 5459)Canadair Regional
American Airlines (AA 5457)
- M
- -
- -
- T
- F
- -
- S

12:27 MHT

19:40 TYS

7Hrs, 13m 1 Stop (DCA)
MHTManchester Airport 12:27 - TYS 19:40 7h 13m 1 Stop (DCA) Washington
MHTManchester Airport 12:27

DCAWashington Ronald Reagan National Airport 17:59
DCAWashington Ronald Reagan National Airport 14:19

TYSKnoxville Airport 19:40
7h 13m (3h 40m)
1 Stop DCA · Washington 3h 40m
American Airlines (AA 5150)Crj 700 Canadair Regional

American Airlines (AA 5484)Crj 700 Canadair Regional
American Airlines (AA 5150)
- -
- -
- -
- T
- F
- -
- S

12:31 MHT

19:40 TYS

7Hrs, 09m 1 Stop (DCA)
MHTManchester Airport 12:31 - TYS 19:40 7h 09m 1 Stop (DCA) Washington
MHTManchester Airport 12:31

DCAWashington Ronald Reagan National Airport 17:59
DCAWashington Ronald Reagan National Airport 14:19

TYSKnoxville Airport 19:40
7h 09m (3h 40m)
1 Stop DCA · Washington 3h 40m
American Airlines (AA 3420)Embraer Emb 175

American Airlines (AA 5484)Crj 700 Canadair Regional
American Airlines (AA 3420)
- M
- -
- -
- -
- -
- -
- -

12:32 MHT

19:40 TYS

7Hrs, 08m 1 Stop (DCA)
MHTManchester Airport 12:32 - TYS 19:40 7h 08m 1 Stop (DCA) Washington
MHTManchester Airport 12:32

DCAWashington Ronald Reagan National Airport 17:59
DCAWashington Ronald Reagan National Airport 14:24

TYSKnoxville Airport 19:40
7h 08m (3h 35m)
1 Stop DCA · Washington 3h 35m
American Airlines (AA 5150)Crj 700 Canadair Regional

American Airlines (AA 5484)Crj 700 Canadair Regional
American Airlines (AA 5150)
- -
- T
- W
- -
- -
- -
- -

13:03 MHT

17:38 TYS

4Hrs, 35m 1 Stop (PHL)
MHTManchester Airport 13:03 - TYS 17:38 4h 35m 1 Stop (PHL) Philadelphia
MHTManchester Airport 13:03

PHLPhiladelphia International Airport 15:40
PHLPhiladelphia International Airport 14:35

TYSKnoxville Airport 17:38
4h 35m (1h 05m)
1 Stop PHL · Philadelphia 1h 05m
American Airlines (AA 5787)Er4 Embraer Rj145 Amazon

American Airlines (AA 5576)Canadair Regional
American Airlines (AA 5787)
- M
- -
- -
- T
- F
- -
- S

17:59 DCA

14:35 PHL

6Hrs, 37m 1 Stop (TYS)
DCAWashington Ronald Reagan National Airport 17:59 - PHL 14:35 6h 37m 1 Stop (TYS) Knoxville
DCAWashington Ronald Reagan National Airport 17:59

MHTManchester Airport 13:03
TYSKnoxville Airport 19:40

PHLPhiladelphia International Airport 14:35
6h 37m (2h 18m)
1 Stop TYS · Knoxville 2h 18m
American Airlines (AA 5484)Crj 700 Canadair Regional

American Airlines (AA 5787)Er4 Embraer Rj145 Amazon
American Airlines (AA 5484)
- M
- T
- W
- T
- F
- -
- S

18:43 CLT

14:35 PHL

6Hrs, 42m 1 Stop (TYS)
CLTCharlotte Airport 18:43 - PHL 14:35 6h 42m 1 Stop (TYS) Knoxville
CLTCharlotte Airport 18:43

MHTManchester Airport 13:03
TYSKnoxville Airport 19:45

PHLPhiladelphia International Airport 14:35
6h 42m (2h 21m)
1 Stop TYS · Knoxville 2h 21m
American Airlines (AA 3119)Airbus

American Airlines (AA 5787)Er4 Embraer Rj145 Amazon
American Airlines (AA 3119)
- -
- -
- -
- -
- F
- -
- S

18:43 CLT

14:35 PHL

6Hrs, 42m 1 Stop (TYS)
CLTCharlotte Airport 18:43 - PHL 14:35 6h 42m 1 Stop (TYS) Knoxville
CLTCharlotte Airport 18:43

MHTManchester Airport 13:03
TYSKnoxville Airport 19:45

PHLPhiladelphia International Airport 14:35
6h 42m (2h 21m)
1 Stop TYS · Knoxville 2h 21m
American Airlines (AA 3119)Airbus

American Airlines (AA 5787)Er4 Embraer Rj145 Amazon
American Airlines (AA 3119)
- M
- -
- -
- T
- -
- -
- -

18:45 CLT

14:35 PHL

6Hrs, 56m 1 Stop (TYS)
CLTCharlotte Airport 18:45 - PHL 14:35 6h 56m 1 Stop (TYS) Knoxville
CLTCharlotte Airport 18:45

MHTManchester Airport 13:03
TYSKnoxville Airport 19:59

PHLPhiladelphia International Airport 14:35
6h 56m (2h 23m)
1 Stop TYS · Knoxville 2h 23m
American Airlines (AA 5206)Canadair Regional

American Airlines (AA 5787)Er4 Embraer Rj145 Amazon
American Airlines (AA 5206)
- -
- T
- W
- -
- -
- S
- -

15:45 MHT

21:41 TYS

5Hrs, 56m 1 Stop (PHL)
MHTManchester Airport 15:45 - TYS 21:41 5h 56m 1 Stop (PHL) Philadelphia
MHTManchester Airport 15:45

PHLPhiladelphia International Airport 19:20
PHLPhiladelphia International Airport 17:24

TYSKnoxville Airport 21:41
5h 56m (1h 56m)
1 Stop PHL · Philadelphia 1h 56m
American Airlines (AA 5437)Crj 700 Canadair Regional

American Airlines (AA 5903)Er4 Embraer Rj145 Amazon
American Airlines (AA 5437)
- M
- T
- W
- T
- F
- S
- S

16:59 MHT

21:37 TYS

4Hrs, 38m 1 Stop (CLT)
MHTManchester Airport 16:59 - TYS 21:37 4h 38m 1 Stop (CLT) Charlotte
MHTManchester Airport 16:59

CLTCharlotte Airport 20:24
CLTCharlotte Airport 19:30

TYSKnoxville Airport 21:37
4h 38m (54m)
1 Stop CLT · Charlotte 54m
American Airlines (AA 5422)Canadair Regional

American Airlines (AA 5292)Canadair Regional
American Airlines (AA 5422)
- M
- T
- W
- T
- F
- S
- S

16:59 MHT

23:31 TYS

6Hrs, 32m 1 Stop (CLT)
MHTManchester Airport 16:59 - TYS 23:31 6h 32m 1 Stop (CLT) Charlotte
MHTManchester Airport 16:59

CLTCharlotte Airport 22:20
CLTCharlotte Airport 19:30

TYSKnoxville Airport 23:31
6h 32m (2h 50m)
1 Stop CLT · Charlotte 2h 50m
American Airlines (AA 5422)Canadair Regional

American Airlines (AA 5019)Canadair Regional
American Airlines (AA 5422)
- M
- -
- -
- T
- F
- -
- S

22:20 CLT

19:15 DCA

6Hrs, 07m 1 Stop (TYS)
CLTCharlotte Airport 22:20 - DCA 19:15 6h 07m 1 Stop (TYS) Knoxville
CLTCharlotte Airport 22:20

MHTManchester Airport 17:24
TYSKnoxville Airport 23:31

DCAWashington Ronald Reagan National Airport 19:15
6h 07m (1h 33m)
1 Stop TYS · Knoxville 1h 33m
American Airlines (AA 5019)Canadair Regional

American Airlines (AA 5338)Canadair Regional
American Airlines (AA 5019)
- M
- -
- -
- T
- F
- -
- S

19:20 MHT

23:31 TYS

4Hrs, 11m 1 Stop (CLT)
MHTManchester Airport 19:20 - TYS 23:31 4h 11m 1 Stop (CLT) Charlotte
MHTManchester Airport 19:20

CLTCharlotte Airport 22:20
CLTCharlotte Airport 21:50

TYSKnoxville Airport 23:31
4h 11m (30m)
1 Stop CLT · Charlotte 30m
American Airlines (AA 5295)Canadair Regional

American Airlines (AA 5019)Canadair Regional
American Airlines (AA 5295)
- M
- -
- -
- T
- F
- -
- S

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How far is Knoxville from Manchester?

The flight distance between Manchester and Knoxville is 1323km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 05:49. The last flight of the day departs at 05:49. See the full list of flight times on Wego.

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